A multi-well microfiltration apparatus and method are provided and feature a
manual
touch-off system for transferring pendent drops hanging from discharge-conduits
of a discharge-conduit array to respective receiving wells or receiving holes of
a corresponding receiving array, with minimum or no cross-contamination between
the discharge conduits, or the receiving wells or receiving holes. The manual touch-off
is achieved by manually shifting a carriage that supports one of the arrays, into
a position whereat pendent drops of fluid hanging from the distal ends of the discharge
conduits contact the inner sidewalls of the corresponding receiving wells or receiving
holes of the receiving array.