A method for inhibiting and/or ameliorating the occurrence of diseases
associated with reactive oxygen species, reactive nitrogen species,
radicals and/or non-radicals in a subject whereby a subject is
administered a carotenoid analog or derivative, either alone or in
combination with another carotenoid analog or derivative, or
co-antioxidant formulation. The analog or derivative is administered such
that the subject's risk of experiencing diseases associated with reactive
oxygen species, reactive nitrogen species, radicals and/or non-radicals
may be thereby reduced. The analog or analog combination may be
administered to a subject for the inhibition and/or amelioration of any
disease that involves production of reactive oxygen species, reactive
nitrogen species, radicals and/or non-radicals. In some embodiments, the
invention may include a chemical compound including an analog or
derivative of a carotenoid. The carotenoid analog or derivative may be
synthetic. The carotenoid analog may include a conjugated polyene with
between 7 to 14 double bonds. The conjugated polyene may include an
acyclic alkene including at least one substituent and/or a cyclic ring
including at least one substituent. In some embodiments, a carotenoid
analog or derivative may include at least one substituent. The
substituent may enhance the solubility of the carotenoid analog or
derivative such that the carotenoid analog or derivative at least
partially dissolves in water.
