There is provided a method of preventing a respiratory infection by administering
an effective amount of an agent for regulating ICAM-1 expression. Also provided
is a composition for the prevention of respiratory infection including an agent
which regulates ICAM expression. method of preventing RSV infection by administering
an effective amount of an agent that interferes with the binding of RSV to ICAM-1.
A method of preventing RSV infection by administering an effective amount of an
agent that down regulates the expression of ICAM-1, thereby decreasing RSV binding
to ICAM-1 is also provided. There is provided a method of treating RSV infection
by administering an effective amount of an agent for down regulating ICAM-1 expression.
A method of blocking RSV-ICAM-1 interaction by administering an effective amount
of agents for blocking ICAM sites of binding is provided. Also provided is a compound
for blocking RSV-ICAM-1 interaction including an agent for blocking ICAM sites
of binding.