Methods and associated materials for transducing mesenchymal stem cells with
a desired nucleic acid. Mesenchymal stem cells are a recently discovered kind of
stem cell for which suitable transfer vehicles are still desired. Typical gene
delivery vehicles such as the adenoviruses or adeno associated viruses have no
particular tropism for mesenchymal stem cells. Also disclosed is gene therapy using
adenoviruses provided with tropism for mesenchymal stem cells.