Devices and methods for reducing, inhibiting, or treating restenosis and
hyperplasia after intravascular intervention are provided. In particular,
the present invention provides luminal prostheses which allow for
sustained or controlled release of at least one therapeutic capable agent
with increased efficacy to selected locations within a patient's
vasculature to reduce restenosis. An intraluminal prosthesis may comprise
an expandable structure and a source adjacent the expandable structure
for releasing the therapeutic capable agent into a body lumen to reduce
smooth muscle cell proliferation.