Novel compounds of formulae (I) to (VIII), which more particularly include
sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives,
sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide
derivatives which are effective platelet ADP receptor inhibitors. These derivatives
may be used in various pharmaceutical compositions, and are particularly effective
for the prevention and/or treatment of cardiovascular diseases, particularly those
diseases related to thrombosis. The invention also relates to a method for preventing
or treating thrombosis in a mammal comprising the step of administering a therapeutically
effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically
acceptable salt thereof.
