The present invention relates to peptidomimetic compounds which inhibit serine
protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease.
As such, they act by interfering with the life cycle of the hepatitis C virus and
are also useful as antiviral agents. The compounds of this invention have a bridged
bicyclic moiety at the P2 position. The invention further relates to compositions
comprising these compounds either for ex vivo use or for administration to a patient
suffering from HCV infection. The invention also relates to methods of treating
an HCV infection in a patient by administering a composition comprising a compound
of this invention.
