The invention relates to the nucleic acid of a novel human MATK-related gene
variant (MATKV) and the polypeptide encoded thereby. The invention also provides
a process for producing the polypeptide encoded by MATKV. The invention further
provides the uses of the nucleic acid of MATKV and the polypeptide encoded thereby
in diagnosing the diseases associated with the deficiency of human MATK gene, in
particular lung cancers, preferably small cell lung cancer.