Substituted cyclic amine metalloprotease inhibitors

   
   

The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). 1 Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.

 
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> Oxamide inhibitors of plasminogen activator inhibitor-1

> Indole compounds

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