The present invention relates to a bone polypeptide, particularly bone
polypeptide-1 and nucleic acid molecules encoding the same. The present
invention provides the human primary sequence of bone polypeptide-1 as
well as sequences of vertebrate homologs. The invention also provides
cell lines engineered to express the cDNA, antibodies to detect its
translation products, and recombinant adenoviruses to deliver an
expressible cDNA into a host. Bone polypeptide-can be utilized to treat
diseases affecting renal and bone functions.
