Methods of treating, preventing and/or managing central nervous system
disorders, such as Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's
Disease) and related syndromes are disclosed. Specific methods encompass
the administration of an immunomodulatory compound of the invention, or a
pharmaceutically acceptable salt, solvate, hydrate, stereoisomer,
clathrate, or prodrug thereof, alone or in combination with a second
active ingredient. Pharmaceutical compositions, single unit dosage forms,
and kits suitable for use in methods of the invention are also disclosed.
