The present invention provides nucleobase oligomers and oligomer complexes
that inhibit expression of an IAP polypeptide, and methods for using them
to induce apoptosis in a cell. The nucleobase oligomers and oligomer
complexes of the present invention may also be used to form
pharmaceutical compositions. The invention also features methods for
enhancing apoptosis in a cell by administering a nucleobase oligomer or
oligomer complex of the invention in combination with a chemotherapeutic
or chemosensitizing agent.
