The invention provides an isolated human Prkag3 promoter. Expression
constructs containing the Prkag3 promoter also are provided, as are
methods of using such expression constructs to direct expression of a
heterologous coding sequence. Host cells containing an expression
construct of the invention are provided, as well as methods of using such
cells to screen for compounds that transcriptionally modulate the
activity of a Prkag3 promoter.