The invention encompasses systems, methods, and apparatus for predicting
and monitoring an individual's response to a therapeutic regimen. The
invention includes multiple virtual patients, an associating subsystem
operable to associate the subject with one or more of the virtual
patients, and a simulation engine operable to apply one or more
experimental protocols to the one or more virtual patients identified
with the subject to generate a set of outputs. The set of outputs can
represent therapeutic efficacy, identify biomarkers for monitoring
therapeutic efficacy, or merely report the status of the biological
system as it represents a particular individual