Antitumoral compositions can comprise as therapeutic agent one or several
immunogenic polypeptides, of which at least one is modified so as to have
a cell location different from its native location. Compositions can be
based on a recombinant vector expressing such an immunogenic polypeptide.
A recombinant vector comprising at least the sequences coding for an
immunogenic polypeptide originating from a precocious and/or tardive
region of a papillomavirus having a modified location and a viral
particle comprising said vector is also described. Finally, therapeutic
uses of such a composition, such a recombinant vector and such a viral
particle are described.
