This invention relates to compounds, compositions, and methods useful for
modulating gastric inhibitory polypeptide (GIP) and/or gastric inhibitory
polypeptide receptor (GIPr) gene expression using short interfering
nucleic acid (siNA) molecules. This invention also relates to compounds,
compositions, and methods useful for modulating the expression and
activity of other genes involved in pathways of gastric inhibitory
polypeptide (GIP) and/or gastric inhibitory polypeptide receptor (GIPr)
gene expression and/or activity by RNA interference (RNAi) using small
nucleic acid molecules. In particular, the instant invention features
small nucleic acid molecules, such as short interfering nucleic acid
(siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA),
micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods
used to modulate the expression of gastric inhibitory polypeptide (GIP)
and/or gastric inhibitory polypeptide receptor (GIPr) genes.
