The present invention relates to novel muteins of human basic fibroblast
growth factor with superagonist properties. Both protein and the
respective encoding nucleic acid species are disclosed. The invention
also embodies vectors and host cells for the propagation of said nucleic
acid sequences and the production of said muteins. Also disclosed are
methods for stimulating cell division, treating a wound, treating
ischemia, treating heart disease, treating neural injury, treating
peripheral vascular disease, treating a gastric ulcer and treating a
duodenal ulcer.
