The present invention comprises a method of protecting organs or tissue susceptible
to reperfusion-induced dysfunction after ischemia. The method comprises parenterally
administering to a patient a therapeutical composition containing natural alpha-1
acid glycoprotein, natural alpha-1 antitrypsin or a mixture thereof. Alternatively,
organ or tissue transplants can be contacted with natural alpha-1 acid glycoprotein,
natural alpha-antitrypsin or mixtures by perfusing or flushing them with a solution
containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or mixtures
thereof in a concentration of 0.1 to 5 g/l.
