Compounds of the formula ##STR1##

useful for the treatment of diseases such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.


< 5-substituted 2-aryl-4-pyrimidinones

< Cis-2,6-disubstituted piperidines for the treatment of psychostimulant abuse and withdrawal, eating disorders, and central nervous system diseases and pathologies

> Spiro[isobenzofuran-1,4-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4-piperidines

> Human uncoupling proteins and polynucleotides encoding the same

~ 00207