An inflatable suspension harness/body jacket and method of use in medical partial weight-bearing therapy. The suspension harness/body jacket is fit onto a patient and has bladders that are inflated sufficiently to achieve a tight conforming fit. Deflating and re-inflating the bladders where necessary to re-achieve the tight conforming fit allows for successful weight-bearing therapy without discontinuing the therapy for an extended period or removing the patient. The suspension harness/body jacket has shoulder straps and jacket portions that may pass through D-rings that, when attached to a frame or other apparatus, provide additional offloading capacity.