The invention concerns amide derivatives of Formula (I), wherein R3 is
(1-6C)alkyl or halogeno; m is 1-3 and R1 is selected from substituents
such as: (A) hydroxy, halogeno, (1-6C)alkyl, (1-6C)alkoxy, aryl, heteroaryl and
heterocyclyl; and (B) di-[(1-6C)alkyl]amino-(1-6C)alkyl, (1-6C)alkoxy-(2-6C)alkoxy,
di-[(1-6C)alkyl]amino-(2-6C)alkoxy, aryloxy, heteroaryloxy, heteroaryl-(1-6C)alkoxy,
heterocyclyloxy and heterocyclyl-(1-6C)alkoxy; p is 0-2 and R2 is a
substituent such as hydroxy and halogeno; q is 0-4; and R4 is aryl or
cycloalkyl which bears 1-3 substituents such as: (C) hydrogen, hydroxy, halogeno
and heterocyclyl; and (D) heteroaryl-(1-6C)alkoxy and heterocyclyl-(1-6C)alkoxy,
provided that a substituent on R4 is selected from paragraph (C) only
if at least one R1 group is selected from paragraph (B); processes for
their preparation, pharmaceutical compositions containing them and their use in
the treatment of diseases or medical conditions mediated by cytokines.