An endoscopic manual control knob which has a knob body proper in the form of a synthetic resin molding. The knob body is largely composed of a ring-like top plate and a peripheral side wall portion fringed along outer periphery of the top plate. The top plate is provided with an aperture to be fitted on a rotatable shaft, and a number of lever portions projecting radially outward from the outer periphery of the top plate at angularly spaced positions. The knob body has an implant block embedded in each one of the lever portions by insert molding.