A two-wire field-mounted process device with multiple isolated channels includes a channel that can be an input channel or an output channel. The given input or output channel can couple to multiple sensors or actuators, respectively. The process device is wholly powered by the two-wire process control loop. The process device includes a controller adapted to measure one or more characteristics of sensors coupled to an input channel and to control actuators coupled to an output channel. The controller can be further adapted to execute a user generated control algorithm relating process input information with process output commands. The process device also includes a loop communicator that is adapted to communicate over the two-wire loop.