This invention discloses an LED multiplex source and a method of using multi-band-type energies from the source for sterilization, bioactivation, and therapy of a targeted body. The LED multiplex source is a pulsed/modulated LED source with at least one different member of the group of pulsed/modulated radiation sources consisting of: an electromagnetic, acoustic, electroluminescent, thermal, and/or magnetic source. The invention also teaches how to convert heat generated by the LED multiplex source into electromagnetic radiation and uses this radiation for sterilization, bioactivation, and therapy. The LED multiplex source is an energy-efficient radiation source, is compact, and also provides sensory feedback to optimize, in real-time, sterilization, bioactivation, and therapy processes. The invented source will replace some of the existing radiation sources and, as well, will open new areas of applications.