Compounds having the formula:
##STR1##
- wherein A4 is N and X is —C(O)— or —CH2—,
are provided, which are useful as modulators of a chemokine receptor and for treatment
of inflammatory and immunoregulatory disorders and diseases. Pharmaceutical compositions
and methods of using these compounds for the treatment of inflammatory and immunoregulatory
disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type
I diabetes, are also provided.
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