A seal on a movable top or bottom plate for use in a chromatography column. The
plate is formed of a flow distributor connected to one or more movement rods that
control the movement of the top plate within a chromatography column. The plate
is formed of two pieces, a flow distributor and a seal plate. The seal plate is
mounted on top of the flow distributor and has a seal that is essentially co-terminal
with the outer edge of the flow distributor. The seal plate is attached to the
flow distributor by one or more pins or threaded bolts and forms a space between
them. The one or more pins contain one or more compression means for biasing the
seal plate against the flow distributor. An opening is formed in the seal plate
for the selective introduction of a pressurized energy source such as compressed
air, gas or hydraulic fluid into the space to overcome the compression means. One
or more seals are arranged between the seal plate and distributor to maintain the
pressurized energy source between the two of them. Optionally the space may contain
a closed bladder or reservoir connected to the opening to contain the pressurized
energy source.