The invention concerns quinazoline and quinoline derivatives of Formula (I) wherein
Q1 includes a quinazoline or quinoline ring optionally substituted with
a group such as halogeno, trifluoromethyl and cyano, or a group of the formula:
Q3—X1— wherein X1 includes a direct
bond and O and Q3 includes aryl, aryl-(1-6C)alkyl, heterocyclyl and
heterocyclyl-(1-6C)alkyl; each of R2, R3 and R5 is
hydrogen or (1-6C)alkyl, provides that one of the parts of groups R2 and
R4 together, R3 and R4 together and R5 and
R4 together forms a bond; R6 is an optionally substituted
group selected from (2-6C) alkenyl, (2-6C) alkynyl, (3-7C)cycloalkyl and (3-7C)
cycloalkenyl, or R6 is a substituted (1-6C) alkyl group; and Q2
includes aryl and aryl-(1-3C)alkyl or a pharmaceutically-acceptable salt
thereof; processes for their preparation, pharmaceutical compositions containing
them and their use in the manufacture of a medicament for use in the prevention
or treatment of T cell mediated diseases or medical conditions in a warm-blooded animal.