This invention relates to a new and distinct variety of strawberry named 'Driscoll Destin.' The variety is similar to the varieties 'Biscayne' and 'Key Largo.' The variety is distinguished from 'Biscayne' and 'Key Largo,' in particular, by its shorter plant height, larger flower diameter, an orange-red external fruit color, greater yield, weak leaf glossiness, very dense stipule pubescence, and a small hollow fruit center.