A method for maintaining the enclosed volume of a sealed package at about ambient
pressure, wherein the package contains a pressurized container comprising a drug,
and an HFA (hydrofluoroalkane) propellant selected from the group consisting of
HFA 134a and HFA p227, or a mixture thereof; wherein the method comprises the steps
of (1) positioning an effective amount of a HFA adsorbent material, and said pressurized
container, within a sealable package; (2) sealing the package so that the pressurized
container and adsorbent are in an enclosed volume within the package at a pressure
equal to about ambient pressure; and (3) adsorbing any leakage of the HFA propellant
into the HFA adsorbent material so as to maintain the enclosed volume at about
ambient pressure.