Compositions and methods are provided for prevention and clinical treatment of various forms of graft-versus-host disease (GVHD) by using inhibitors of adenosine deaminase (ADA). In particular, various formulations and dosing regimens of ADA inhibitors such as pentostatin are provided for the treatment of humans in vivo as well as for ex vivo conditioning of organ transplants in order to specifically suppress T-lymphocyte mediated immune responses while minimizing systemic toxicity of the drug.


< Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof

< Peptide (VIRIP) which inhibits a circulating virus in humans and the use thereof

> HIV integrase inhibitors

> Bicyclo 4.4.0 antiviral derivatives

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