The present invention relates to novel cytoplasmic tyrosine kinases isolated from megakaryoctyes (megakaryocyte kinases or MKKs) which are involved in cellular signal transduction pathways and to the use of these novel proteins in the diagnosis and treatment of disease. The present invention further relates to specific megakaryocyte kinases, designated MKK1, MKK2, and MKK3, and their use as diagnostic and therapeutic agents.


< Corticotropin releasing factor antagonists

< 25312, a novel human agmatinase-like homolog

> Claspin proteins and methods of use thereof

> Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof

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