The present invention provides compounds of formula I ##STR00001## and pharmaceutically acceptable salts thereof.The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.

 
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< Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof

< Camptothecin intermediates and prodrugs and methods of preparation thereof

> Pharmaceutically active compounds having a tricyclic pyrazolotriazolopyrimidine ring structure and methods of use

> Highly lipophilic camptothecin intermediates and prodrugs and methods of preparation thereof
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