The present invention relates to novel oligonucleotide sequences and also
to derivatives thereof.These novel oligonucleotide sequences are capable
of hybridizing specifically with the gene or with a product of the gene
encoding tyrosinase, or with the gene or a product of the gene encoding
tyrosinase-related-protein 1 (TRP-1).The present invention also relates
to the use of these novel oligonucleotide sequences as a depigmenting or
bleaching agent in a cosmetic composition or in a dermatological
composition.