An antimicrobial solution is provided for use in the cleaning of dentures and toothbrushes, as well as, for use as an oral mouthwash and/or a general disinfectant. The primary active ingredients of the present invention include an approximately 4.5% solution of hydrogen peroxide as an antibacterial agent and sodium lauryl sulfate as a cleansing agent. The present invention is mixed and maintained in liquid form. Additional ingredients are included to ensure the activation of the various antibacterial or cleansing agents. The present invention overcomes the problems with presently available denture cleansers because it does not require the use of hot, warm, or even cold water to activate the cleansing agent.