This invention provides a total synthesis of Merrillactone and Merrilactone analogues for use as neurotrophic agents in the treatment of neurodegenerative diseases. The invention also provides intermediates for use in the synthesis of Merrilactone and its analogues.

 
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> Substituted aryl thioureas and related compounds; inhibitors of viral replication

> Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
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