This invention relates to novel adenoviruses useful in the production of high titers of recombinant adeno-associated virus (rAAV) comprising a foreign DNA insert and methods of making these adenoviruses. The adenovirus comprises the AAV rep gene in which the p5 promoter is replaced by a minimal promoter or by no promoter. The invention also provides methods of producing high levels of rAAV as a substantially homogenous preparation and composition of rAAV.

 
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< Selection of coordination geometry to adjust water exchange rates of paramagnetic metal ion-based macrocyclic contrast agents

< Dosage forms having a barrier layer to laser ablation

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> Recombinant human SM-11044-binding receptor proteins exhibiting ligand-binding activities, and their uses
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