A gain stage in a sense amplifier receives an input signal representing a stored value and senses if the input signal is less than or not less than a reference signal and generates an output signal indicative of a first state when the input signal is less than the reference signal and an output signal indicative of a second state when the input signal is not less than the reference signal. The gain stage further comprises an integrated latch configured to latch the output signal in either the first or second state. Additionally, a controller operates a sense amplifier having multiple operating modes. Sample mode switch logic causes the sense amplifier to sample a first voltage applied to the sense amplifier's input and hold and compare mode switch logic causes the sense amplifier to hold the first voltage for comparison with a second voltage applied to the sense amplifier's input.