A surgical instrument for applying an anastomotic ring device comprises a handle connected to an anastomotic ring deployment mechanism by a shaft. The shaft has at least one torsion member that is capable of communicating a torsional actuating force from the handle to the ring deployment mechanism. The ring deployment mechanism is configured to actuate in response to torsional actuating force communicated from the torsion member. A threaded shaft or rod may be positioned in the ring deployment mechanism to effect actuation of the ring deployment mechanism in response to torsion.

 
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> METHOD FOR SYSTEMIC DRUG DELIVERY THROUGH THE NAIL

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