Novel nucleic acid sequences encoding lepidoptera calcium channel subunits, and recombinant expressions and host cells comprising the same are disclosed. Isolated lepidoptera calcium channel subunits, host cells expressing a lepidoptera calcium channel subunits, methods of producing the lepidoptera calcium channel subunits and antibodies specific for the lepidoptera calcium channel subunits are also disclosed. Methods of identifying modulators and/or inhibitors of lepidoptera calcium channels are disclosed