A method and apparatus for determining the stability of dispersions and
emulsions accelerates the onset of significant particle agglomeration in
a sample by stressing the sample by reducing the height of the
interparticle potential energy barrier between the particles. This is
achieved by adding one or more of three stress factors: changing the pH
of the sample to reduce the surface charge on the particles; adding an
adsorbing electrolyte so that ions of the appropriate charge are adsorbed
onto the surfaces of the particles to reduce the net charge on the
particles; and applying a monovalent, divalent, or trivalent salt to
partially screen electrostatic repulsions between the charged particles.
In a preferred embodiment, the increase in agglomeration is detected with
single particle detection, such as SPOS, to generate a PSD from which a
figure of merit is derived. Another embodiment detects turbidity or light
scattering to generate a value X indicative of the extent of
agglomeration.