An integrated post-amplifier and laser driver assembly is provided that is implemented as a single integrated circuit and is configured to implement various effects, such as polarity control, concerning data signals received by an optical transceiver in conjunction with which the integrated post-amplifier and laser driver assembly is employed. The data signal polarity control is implemented, both in the post-amplifier assembly and the laser driver assembly, by an amplifier that changes the polarity of the data signal by modifying a relationship between first and second propagation paths of the data signal. The data signal polarity control is typically performed in response to a multiplexed digital control signal received at a digital control interface of the integrated post-amplifier and laser driver assembly.