Substituted thienoimidazoles with a backbone structure of formula I or II: ##STR00001## These substituted thienoimidazoles are useful in prevention or treatment of various disorders, including respiratory disorders.

 
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> 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2, 4-dione and analogues as inhibitors of macrophage elastase
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