A description is given of 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines of formula (I) and of their use as herbicides. ##STR00001## In this formula (I) R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are various radicals, A is an aromatic or heteroaromatic radical, and Z is a nitrogen or carbon atom.

 
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> Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof

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