The gamma adjustment allows the luminance for the sub-pixel arrangement to match the non-linear gamma response of the human eye's luminance channel, while the chrominance can match the linear response of the human eye's chrominance channels. The gamma correction allows the algorithms to operate independently of the actual gamma of a display device. The sub-pixel rendering techniques disclosed with gamma adjustment can be optimized for a display device gamma to improve response time, dot inversion balance, and contrast because gamma correction and compensation of the sub-pixel rendering algorithm provides the desired gamma through sub-pixel rendering. These techniques can adhere to any specified gamma transfer curve.