Method of regenerating a glycol solution containing water, hydrocarbons and salts. The glycol solution is expanded in drum (2), then distilled in column (7). The concentrated glycol collected at the level of reboiler (8) is placed under vacuum to vaporize the water and to precipitate the salts. The salts are separated from the glycol in separation device (13). The concentrated glycol freed of the salts is stored in capacity (16).