The present invention is related a method and system for irradiating a target location or material with high-amplitude narrow pulses of electromagnetic (EM) energy at a periodic or quasi-periodic rate. The method and system comprises generating at least three electromagnetic signals simultaneously in space from at least three sources, each signal having the same repetition rate and a different frequency, and directing each signal to at least one predetermined target, and adjusting the phase of each signal, so that its peak field occurs at the same instant as the occurrence of the peak fields of all the signals at the target.