Epoxidised oil, epoxidised wax or epoxidised fatty acid ester recovered from Vernonia Galamensis seeds provide topical medicament preparations which are effective in preventing and treating various different forms of skin diseases, skin lesions and wounds. These epoxidised oil, epoxidised wax or epoxidised fatty acid ester recovered from Vernonia Galamensis seeds can also be bound to bio-available molecules, such as proteins, to modify the effect of the bio-available molecules when administered to the human body.