A composition for reducing the weight of a human. The composition is provided in the form of a capsule comprising an effective amount of capsaicin and/or analogs thereof, L-tyrosine, supplemental caffeine and/or and analogs thereof, green tea extract containing catechin and caffeine, and embodiments which include calcium. The invention is also directed toward methods for reducing and maintaining weight of a human using the composition.

 
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> Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer

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