A programmable analog circuit includes a plurality of analog inputs, a differential analog buffer, a digital-to-analog converter, an analog-to-digital converter, and an operational amplifier having an inverting input and a non-inverting input. An analog switching network is coupled between the plurality of analog inputs, the differential analog buffer, the digital-to-analog converter, the analog-to-digital converter, and the operational amplifier and is configured to allow programmable connections from any of the plurality of analog inputs, the differential analog buffer, and the digital-to-analog converter to the inverting input and a non-inverting input; of the operational amplifier. An array of programmable logic is programmably coupled to the input to the digital-to-analog converter and the output of the analog-to-digital converter.