Systems and methods for performance improvements in digital switching amplifiers using simulation-based feedback. In one embodiment, a digital pulse width modulation (PWM) amplifier includes a signal processing plant configured to receive and process an input audio signal. The amplifier also includes a simulator configured to model processing of audio signals by the plant. The outputs of the plant and the simulator are provided to a subtractor, the output of which is then added to the input audio signal as feedback. The plant may consist of a modulator and power switch, a noise shaper, or any other type of plant. An analog-to-digital converter (ADC) may be provided to convert the output audio signal to a digital signal for input to the subtractor. Filtering may be implemented before or after the ADC, and a decimator may be placed after the ADC if it is an oversampling ADC.